Most recently, Swiss pharma behemoth Novartis unveiled plans to build a new radioligand therapy manufacturing facility in Winter Park, Florida, as part of a $23 billion U.S. investment pledge announced in April 2025. Number of monthly newly-appeared and disappeared listings in the marketplaces Agora and Evolution. To evaluate the aforementioned methods for extracting properties, we randomly chose 1000 listings for each property and manually annotated the properties as ground truth. We evaluated our method on our annotated data set, which yields an accuracy of over 90% for each property extraction, as shown in Table 5.
Xylazine and wound care
Homeless and Addiction Recovery Treatment Hubs (HART Hubs): Reference Document, January 2025
This can occur when benefits investigation is ongoing or when a servicing pharmacy is no longer in network. The hub will then take over filling the prescription while the benefits are verified and then triage the script to the correct pharmacy. These programs help to establish a patient on therapy, maintain patient engagement with therapy, and, in turn, drive patient compliance to therapy. This is accomplished through various means, such as online web portals, social media integration, telephone outreach, etc. Contributors with living/lived expertise of drug use and active students receive a $100 stipend per accepted submission, sent via e-transfer.
Pakistan Pancreatic And Bile Duct Cancer Market data and reports
The results provide insight into opioid trading in the anonymous markets and forums and may prove an effective mitigation data point for illuminating the opioid supply chain. The Drug Hub editorial team is made up of people who use(d) drugs, students, researchers, and healthcare professionals who work with marginalized and criminalized communities. Note that we should not overestimate the number of suppliers and buyers given the number of IDs found in this research, but we regarded it as the upper-bounded number of the opioid suppliers and buyers. This is because the same user could have different IDs, and the same ID in different marketplaces can point to different users. Owing to the anonymity of the underground marketplaces and forums, there exists no ground truth to link users with their IDs. Our goal here was to identify anonymous forum posts with the topics of opioid commodity promotion (eg, listing promotion) and review (eg, report fake opioid vendors).
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But this brave new world of darknet drug-dealing is fraught with pitfalls and slippery slopes. 🚨 DrugHub is the leading darknet marketplace for verifiedvendors, over 100,000+ listings, over 500,000 active users, and more than 4,000 trusted vendors. Launched in August 2023 bythe legendary team behind White House Market, DrugHub has quickly become the topdarknet market globally. Law enforcement agencies around the world seized an online marketplace and arrested nearly 300 people allegedly involved in buying and selling drugs, European Union law enforcement agency Europol said Tuesday.
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In addition to patient services, benefits investigation, and REMS reporting, a hub must understand and consider the manufacturer’s drug distribution strategy. Specialty medications are often expensive products with limited distribution models that service smaller patient populations and have cold chain storage requirements. Like the service they provide, hubs can be complex and difficult to define. Historically hubs largely provided reimbursement services, helping patients and providers navigate the process to obtain reimbursement for expensive specialty medications. The in-depth research on specialty drug hub Services underscores their pivotal role in enhancing medication adherence and patient health outcomes.
Fourcast – Four Counties Addictions Services Team (Peterborough)
A bilateral treaty between the UAE and the United States allows for the extradition of individuals involved in criminal activities, making DrugHub’s choice of location a precarious gamble. Additionally, DrugHub provides vendors with access to private mirrors, adding an extra layer of security against unauthorized access. Learn how we’re helping create safer communities and supporting people struggling with addiction and mental health issues by approving 18 new HART Hubs. Unlike other markets that hide fees in vendor pricing, Drug Hub is transparent. Customers pay a standard 5% commission that can be adjusted based on account activity and volume.
Why Choose DrugHub Market?
When staff mediation is needed, saved copies of original listings ensure accurate resolution based on the terms at time of purchase. In case of marketplace downtime or critical issues preventing normal support access, check this clearnet website for announcements. We will post updates regarding extended downtime, security incidents, or migration notices. The spokesperson explained to Global News that each hub will address its own “locally identified gaps” in mental health and addictions by “leveraging an integrated approach” and co-locating with other services. “That doesn’t work — I know, I’ve dealt with it within our family, I’ve dealt with it within our community,” Ford said of supervised consumption sites at an unrelated event on Monday. The government also unveiled plans to stop other supervised drug injection sites from opening in Ontario, going against its own expert advice but citing rising crime and complaints from neighbours.
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We used the metrics of precision and recall to compare the performance of different topic modeling methods. As shown in Table 4, our results indicate that our approach significantly outperforms MALLET and the baseline model in terms of both precision and average recall. Data set summary of marketplaces and forums that were collected for this study. The geographic landscape of the Pancreatic And Bile Duct Cancer Drug Market reveals distinct growth trajectories across major regions, shaped by variations in industrial maturity, technology adoption, and investment intensity. North America continues to dominate the market, supported by a robust technological ecosystem, early adoption of advanced solutions, and sustained investments in innovation and automation.
Ministry of Health
Drug Hub is a revolutionary XMR-only darknet marketplace built from the ground up with security, privacy, and user experience as top priorities. Our platform offers a unique approach to anonymous commerce with innovative features that set us apart from traditional darknet markets. The aforementioned hub services allow the manufacturer to positively affect the patient journey by ensuring efficient distribution of medication and improving patient compliance. Knowledge of these services helps one better understand the importance of hubs and the important role they play in specialty pharmacy. "We have heard loud and clear from families across Ontario that drug injection sites near schools and child-care centres are making our communities less safe," Jones said in a statement, adding the hubs will improve access to mental health and addiction services.
“Go Cry on dread about it” — DrugHub’s Administration
- From our measurement, we concluded that anonymous online marketplaces and forums provided easy-access platforms for global opioid supply.
- Finally, in the model refining stage, the model is trained for other 2 iterations using the same objective function.
- These background papers were commissioned by the EMCDDA and Europol to provide background information to inform and contribute to the drafting of the main report.
- However, the views, interpretations and conclusions set out in this publication are those of the author and are not necessarily those of the EMCDDA, Europol or their partners, any EU Member State or any agency or institution of the European Union.
- In the meantime, these 2 vectors are still comparable because they are used together in the neural network to train a single skip-gram model for predicting the surrounding windows of context words.
In Greece, the souvlatzidiko (souvlaki shop) is far more than a fast food joint; it is a cornerstone of daily social life and a true cultural landmark. These neighborhood hubs serve as meeting points where people of all ages and backgrounds gather for a quick, affordable, and deeply satisfying meal. For a platform operating in a space where privacy is paramount, every detail matters.
In our study, we found that 23.78% (9896/41,614) listings and traces were identified with the help of 58 opioid jargons (Table 2). Among them, suboxone and subutex medicines are most frequently mentioned by 2917 times in listings and traces in 10 platforms, followed by roxy series (ie, roxy, roxi, roxies, and roxys) with 2022 times and Lean with 1256 times. Both K9 and M30 were mostly found in Darkbay, within 384 listings in the year 2020, whereas Lean appeared 141 times in Empire listings. HUB meticulously crafts its targeted marketing campaigns to highlight specific applications of organoid technology to accelerate and improve drug testing. The company’s proactive approach to using digital platforms for outreach has played a crucial role in demystifying complex scientific processes and showcasing the tangible benefits of organoids in drug discovery and development. A steering committee made up of senior executives from both organizations will oversee the execution of the new development hub.
As you can see DrugHub.link & DrugHub.su use the same IP address although it might seems suspicious that drughub.su would be seen using Cloudflare as of Today & DrugHub.link would be seen using an IP that was never updated between today and the November 25th 2024. The Ministry of Health works to help people stay healthy, delivering high-quality care when they need it and protecting the health system for future generations. No signin required to browse listings, search products, or check out vendors. Access your account using only your PGP key with enforced two-factor authentication via PGP signatures. Drug Hub operates a private Jabber server for push notifications and optional vendor communication. Jabber details are provided in your account settings after registration.
Primary Marketplace Link
In early 2025, the company broke ground on a $2 billion manufacturing facility project in Wilson. The drugmaker followed that up with a $2 billion deal in September for manufacturing space at Fujifilm Biotechnologies’ Holly Springs location. It also recently announced plans to build a second multibillion-dollar facility in Wilson. That dollar amount continues to tick up, with drugmakers announcing new projects at a steady clip.
He tried 157 drugs
Harm reduction advocates have condemned the move to shutter supervised consumption sites, saying it will put lives at risk and only move drug use into public spaces. More than 2,600 Ontarians died in 2023 due to overdoses, the vast majority due to opioid toxicity. Supervised consumption sites impacted by the bill were given an option to apply to become HART hubs, and the nine facilities approved by the province will transition to the new model of care by March 31, the date they were slated to shut down.
From souvlaki to seized drugs: Drapetsona shop turns criminal spotlight
Adding to the intrigue was DrugHub’s decision to use Base64 encoding for storing and displaying multimedia. While this approach can offer certain advantages, such as reducing the need for external storage, it comes at the cost of increased file sizes—a 33% overhead, to be precise. This inefficiency was not just a technical curiosity but a potential red flag about the team’s understanding of optimal infrastructure design. In the highly competitive and precarious world of darknet marketplaces, such decisions can be the difference between thriving and imploding. If you value privacy and security in your darknet transactions, DrugHub Market is a strong contender.
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Recent years have witnessed the trend of studying opioid use disorders using anonymous marketplaces and forums data [5,8,10] and public social media data (eg, Twitter and Instagram) [11-14]. Gilbert et al [15] described changes in the conceptualizations, techniques, and structures of opioid supply chains and illustrated the diversity of transactions beyond the traditionally linear conceptualizations of cartel-based distribution models. Dasgupta et al [18] collected opioid listings on Silk Road to analyze the prices of diverted prescription opioids. Duxbury et al [6] evaluated the role of trust in online drug markets by applying exponential random graph modelling to underground marketplace transactions. The results show that vendors’ trustworthiness is a better predictor of vendor selection than product diversity or affordability. Considering social media data (eg, Twitter and Instagram), Nasralah et al [14] proposed a text mining framework to collect opioid data from social media and analyzed the most discussed topics to profile the opioid epidemic and crisis.
- The government also unveiled plans to stop other supervised drug injection sites from opening in Ontario, going against its own expert advice but citing rising crime and complaints from neighbours.
- Quick Reply system allows vendors to handle common questions efficiently.
- We found that 182 opioid supplier IDs appeared in both the marketplaces Evolution and Agora from January 2014 to July 2015.
- Pharmacy benefits managers (PBMs) are working with employers to cover these medications through prior authorization models.
- The rising adoption of personalized medicine and innovative drug delivery systems further contribute to market expansion.
- Primary support is provided through the marketplace ticketing system accessible after login.
- However, the pharmacist is concerned the most with one stakeholder in particular—the patient.
Nineteen new addiction treatment hubs will be operational in Ontario before 10 supervised consumption sites are forced to close their doors in March, the Ford government is promising. Hopefully, this has helped to illuminate some of the mystery behind hubs and show how they work to ease the specialty process for some patients. Hub services are most often created for medications that have a complicated path into the patient’s hands. Finally, hub services exist to provide patients, providers, and pharmacies with visibility to co-pay assistance programs. When a hub is operated by a pharmaceutical company, the hub can work with the pharmacy to provide patients with manufacturer co-pay assistance.
- Vendors receive fair treatment with competitive fee structures and no hidden charges.
- A total of 248,359 listings from 10 anonymous online marketplaces and 1,138,961 traces (ie, threads of posts) from 6 underground forums were collected.
- If true, this would not only spell disaster for the platform’s users but also serve as a stark reminder of the stakes involved in operating within this clandestine realm.
- Note that data for 2020 only included data from January to March; price per gram is in US $.
- In this way, we generated a rich underground marketplace opioid vocabulary of 311 opioid keywords with 13 categories.
- Its privacy-first approach ensures that users can transact with confidence, while the private vendor mirrors provide additional protection for vendors.
Co-occurrence of the same opioid suppliers across different anonymous marketplaces. Market Research Intellect (MRI) is a trusted provider of comprehensive market intelligence, delivering actionable insights that enable businesses to make informed, strategic decisions. With a focus on accuracy, depth, and relevance, we specialize in analyzing global markets across diverse industries including healthcare, technology, chemicals, consumer goods, energy, and more.
The breadth of the darknet’s product offering, combined with the relatively low barrier to entry, creates gateways to novel drug-using behaviours, where people try new substances just because they’ve suddenly been made available to them. Learn how we’re keeping our communities safer and improving access to mental health through the transition of nine supervised drug injection sites into HART Hubs. Become part of the #1 darknet marketplace trusted by over 500,000 users and 100k+ listings. Last month, a social services agency in Toronto launched a legal challenge against the law limiting supervise consumption sites, arguing it infringes on the Charter rights to life, liberty and security of person.
We found evidence through extensive analyses of the anonymous online market of pervasive supply, which fuels the international opioid epidemic. Nontraditional methods, as presented here by studying the online supply chain, present a novel approach for governmental and other large-scale solutions. When interpreted by professionals, our initial results demonstrate useful findings and may be used downstream by law enforcement and public policy makers for impactful structural interventions to the opioid crisis. Although a large body of current research is focused on pathways for treatment of opioid use disorder and analyzing deaths per treatment capacity of substance use providers, these research areas are limited to the demand side of the opioid epidemic [40,41]. We believe that the findings and pattern analyses presented here, which place concentration on the supply side, might suggest a new direction to focus and will serve as a useful complement to current research conducted within the domain of addiction medicine. In total, we collected 248,359 listings from 10 anonymous online marketplaces and 1,138,961 traces (ie, threads of posts) from 6 underground forums.